Even though Lloyd Braun kept telling Jerry and others that saying serenity now was not helping anything, they kept doing it. He tried to tell them that it was just bottling things up inside and one day they would crack under the pressure. Of course, no one listened and they just kept saying the phrase.
In the end, it shows that Kramer after practicing "serenity now" just finally had taken too much in his life and he cracked. The next thing we see in this episode is that he is smashing all the computers that George had stored in his apartment.
We act the same way in our lives. We try to say "serenity now" through all types of methods such as positive thinking, praying, meditation, alternative new age practices, drinking, drugs and whatever else you can name here. Some of these things might be considered good things, but in many ways if they are done without a true mind body connection, it is just shouting into the wind.
